Lecturer in Medical Statistics
Before joining the School of Medicine as a Lecturer in Medical Statistics, I held teaching positions at both Durham University and the University of Sunderland. During this time, I gained extensive experience delivering and coordinating a wide range of statistics and mathematics modules, from foundation to master's level.
In 2024, I completed a PhD in Medical Statistics under the supervision of Professor Scott Wilkes, where my research focused on treating subclinical hypothyroidism in an ageing population. This work was funded by the National Institute for Health Research Applied Research Collaboration for the North East and North Cumbria.
I also hold an undergraduate degree in Mathematics and a master's in Mathematical Biology from the University of York.
Teaching and supervision
Research
My research interests focus on applying causal inference methods, including propensity score matching and inverse probability weighting, to observational data. I primarily conduct emulated target trials and cohort studies, comparing the results of these study designs to evaluate their consistency.
I am currently engaged in research focused on the prescribing of levothyroxine, in collaboration with Newcastle University, as well as modelling emergency department wait times in Scotland, in partnership with the University of Edinburgh.
Publications
Article
Holley, Mia, Razvi, Salman, Farooq, Mohammed Saif, Dew, Rosie, Maxwell, Ian and Wilkes, Scott (2024) Cardiovascular and bone health outcomes in older people with subclinical hypothyroidism treated with levothyroxine: a systematic review and meta-analysis. Systematic Reviews, 13 (123). p. 211. ISSN 2046-4053
Holley, Mia, Razvi, Salman, Farooq, Mohammed Saif, Dew, Rosie, Maxwell, Ian and Wilkes, Scott (2024) Cardiovascular and bone health outcomes in older people with subclinical hypothyroidism treated with levothyroxine: a systematic review and meta-analysis. Systematic reviews, 13 (123). ISSN 2046-4053
Holley, Mia, Razvi, Salman, Dew, Rosie, Maxwell, Ian and Wilkes, Scott (2023) Assessing the Cardiovascular Effects of Levothyroxine Use in an Ageing United Kingdom population (ACEL-UK) protocol: a cohort and target trial emulation study. BMC Endocrine Disorders, 16 (43). ISSN 1472-6823
Conference or Workshop Item
Holley, Mia, Razvi, Salman, Dew, Rosie, Maxwell, Ian and Wilkes, Scott (2024) Assessing the effects of levothyroxine use in an ageing United Kingdom population. In: European Conference on Computational Biology 2024, 16-20 Sep 2024, Logomo, Turku, Finland. (Unpublished)
Holley, Mia, Razvi, Salman, Dew, Rosie, Maxwell, Ian and Wilkes, Scott (2023) Cardiovascular and bone health outcomes in elderly subclinical hypothyroid patients: a systematic review and meta-analysis. In: Royal Statistical Society International Conference 2023, 04-07 Sep 2023, Harrogate, United Kingdom.
Holley, Mia, Razvi, Salman, Dew, Rosie, Maxwell, Ian and Wilkes, Scott (2023) Consequences of Over-Diagnosing Hypothyroidism in an Ageing United Kingdom population (CODHA UK). In: Society for Academic Primary Care 51st Annual Scientific Meeting, 18-20 July 2023, Brighton, United Kingdom. (Unpublished)
Thesis
Holley, Mia (2024) Assessing the Cardiovascular, Bone Health and All-Cause Mortality Effects of Levothyroxine Use in an Ageing United Kingdom Population (ACEL-UK). Doctoral thesis, University of Sunderland.
I am a Fellow of the Royal Statistical Society, a Member of the International Society for Computational Biology, an Academic Member of the Society for Academic Primary Care, and an Associate Member of the Institute of Mathematics and its Applications.