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Dr Noel Carter


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Associate Professor in Molecular Biology

I have been teaching at the University since 2002. I recently took up the post of Programme Leader for BSc (Hons) Biomedical Science. My other duties include being the Faculty Biological Safety Officer. 


Teaching and supervision

I teach primarily on BSc (Hons) Biomedical Science but also contribute to teaching on BSc (Hons) Biopharmaceutical Science and various masters courses. The focus of my teaching is cell and molecular biology across a range of modules.

Research interests for potential research students

I am interested in research projects in the area of transplantation and basic cell biology, in particular those with a strong molecular biology component.

Research

My PhD was part of an EU/Japanese project to sequence the genome of Bacillus subtilis followed by a post-doctoral position at Newcastle University working on functional analysis of the B. subtilis genome.

This was then followed by a post-doctoral position working in the area of inflammation conducting research on chemokine/glycosaminoglycan interactions, before taking up a lectureship at the University of Sunderland in 2002.

The main focus of my research centres around increasing the available donor pool for organ transplantation by improving the outcome of organs from donors which previously have been declined for use. This work is in collaboration with Prof. David Talbot, consultant transplant surgeon, at the Freeman Hospital.

My other areas of research include proteomic analysis of the orphan disease cystinosis. I currently have PhD students working on projects investigating mechanisms that regulate cell proliferation and protein drug interactions.

Publications

Number of items: 42.

Article

Ben Kayale, Lilahom, Ling, Jonathan, Henderson, Emily and Carter, Noel (2020) The influence of cultural attitudes to nut exposure on reported nut allergy: A pilot cross sectional study. PLOS ONE, 15 (6). e0234846. ISSN 1932-6203

Sevinc, Mustafa, Stamp, Susan, Ling, Jonathan, Carter, Noel, Talbot, David and Sheerin, Neil. S (2019) Comparison of the outcome of kidney transplantation after pulsatile or continuous ex vivo hypothermic machine perfusion of kidneys donated after cardiac death: analysis of kidney pairs. Transplantation Proceedings, 51 (6). pp. 1785-1790. ISSN 0041-1345

Sevince, M, Stamp, S, Ling, Jonathan, Carter, Noel, Talbot, D and Sherin, N (2016) Ex Vivo Perfusion Characteristics of Donation After Cardiac Death Kidneys Predict Long-Term Graft Survival. Transplantation Proceedings, 48 (10). pp. 3251-3260. ISSN 0041-1345

Forgham, Helen, Johnson, Darren, Carter, Noel, Veuger, Stephany and Carr-Wilkinson, Jane (2015) Stem Cell Markers in Neuroblastoma—An Emerging Role for LGR5. Frontiers in Cell and Developmental Biology, 3 (77). ISSN 2296-634X

Khurram, Muhammad A, Stamp, Susan, Sheerin, Neil S, Rix, David, Cunningham, Anne, Carter, Noel and Talbot, David (2015) Behaviour of transplanted tumours and role of matching in rejection. Transplant Immunology, 32 (2). pp. 121-125. ISSN 0966 3274

Reddy, Mettu, Carter, Noel, Cunningham, Anne, Shaw, J. and Talbot, D (2014) Portal Venous Oxygen Persufflation of the Donation after Cardiac Death pancreas in a rat model is superior to static cold storage and hypothermic machine perfusion. Transplant International, 27 (6). pp. 634-639. ISSN 1432-2277

Mownah, O.A., Khurram, M.A., Kanwar, A., Stamp, S., Rees, D., Brassil, J., Majo, J., Dark, J.H., Carter, Noel and Talbot, D (2014) Development of an ex vivo technique to achieve reanimation of hearts sourced from a porcine donation after circulatory death model. Journal of Surgical Research, 189 (2). pp. 326-334. ISSN 0022-4804

Coad, Laura, Carter, Noel and Ling, Jonathan (2013) Attitudes of young adults from the UK towards organ donation and transplantation. Transplantation Research, 2 (9). ISSN 2047-1440

Niesman, I R and Carter, Noel (2013) Microglia provide unexplored avenues to attenuate cognitive decline following isoflurane exposure in susceptible young and elderly patients: A critical review of TREM2-DAP12 function and therapeutic potential. OA Anaesthetics, 1 (1). p. 10. ISSN 2052-7853

Tan, H W, Weir, B S, Carter, Noel, Heenan, P B, Ridgway, H J, James, E K, Sprent, J I, Young, P W and Mitchell, A (2012) Rhizobia with 16S rRNA and nifH Similar to Mesorhizobium huakuii but Novel recA, glnII, nodA and nodC Genes Are Symbionts of New Zealand Carmichaelinae. PLOS One, 7 (10). e47677. ISSN 1932-6203

Wilson, Colin, Wyrley-Birch, H, Vijayanand, D, Lee, A, Carter, Noel, Haswell, Malcolm, Cunningham, Anne and Talbot, D (2012) The influence of perfusion solution on renal graft viability assessment. Transplantation Research, 1 (18). ISSN 2047-1440

Khurram, M A, Mownah, O A, Ray, C, Kanwar, A, Carter, Noel, Brassil, J, Rees, D, Stamp, S, Dark, J H and Talbot, D (2011) An Ex Vivo Model For Reanimating Porcine Hearts Sourced From Donors After Cardiac Death. Transplant International, 24 (s2). pp. 269-270. ISSN 1432-2277

Ray, C, Khurram, M, Mownah, O, Kanwar, A, Stamp, S, Brassil, J, Rees, D, Philipson, K, Peaston, R, White, K and Carter, Noel (2011) A Novel Perfusion Fluid for DCD Donor Kidneys; Better as a Flush or a Storage Medium? Transplant International, 24 (s2). pp. 320-321. ISSN 1432-2277

Khurram, M A, Mownah, O A, Ray, C, Kanwar, A, Carter, Noel, Rees, D, Brassil, J, Stamp, S, Dark, J H and Talbot, D (2011) Donation After Cardiac Death: Can Hearts be Successfully Reanimated? Transplant International, 24 (s2). p. 171. ISSN 1432-2277

Kanwar, A, Ray, C, Noormohammed, S, Khurram, M A, Stamp, S, Libbrecht, L, Monbaliu, D, Peaston, R, Kesteven, P and Carter, Noel (2011) Extra Corporeal Memberane Oxygenation (ECMO) Vs Cold Preservation (CP) in Porcine Donation after Cardiac Death (DCD) Category-2 Donor Livers. Transplant International, 24 (s2). p. 85. ISSN 1432-2277

Ray, C, Kanwar, A, Noormohamed, M S, Ray, S, Stamp, S, Sohrabi, Soroush, Novarro, A P, Wood, K, Whitehouse, Kim, Peaston, R and Carter, Noel (2011) Porcine Model of Extra-Corporeal Membrane Oxygenation (ECMO) in the Uncontrolled Donation after Cardiac Death (DCD) Donor; the Effect on Renal Viability. Transplant International, 24 (s2). pp. 10-11. ISSN 1432-2277

Mownah, O A, Khurram, M A, Ray, C, Majo, J, Carter, Noel, Brassil, J, Peaston, R, Phillipson, K, Stamp, S and Dark, J H (2011) Preservation of Donation After Cardiac Death Hearts Using Oxygenated, Hypothermic Machine Perfusion. Transplant International, 24 (s2). p. 269. ISSN 1432-2277

Mownah, O A, Khurram, M A, Ray, C, Carter, Noel, Peaston, R, Phillipson, K, Gibbs, K, Gardener, K, Stamp, S and Dark, J H (2011) Using Dialysis For Prolonged Ex Vivo Warm Reperfusion of DCD Hearts. Transplant International, 24 (s2). pp. 171-172. ISSN 1432-2277

Kanwar, A, Khurram, M, Stamp, S, El-Asir, L, Wyrley-Birch, H, Gok, M, Shenton, B, Reddy, Mettu, Cunningham, Anne and Carter, Noel (2010) Current Long Term Outcomes in Controlled and Uncontrolled Non Heart Beating Donor (NHBD) Kidneys - A Five Year Follow up Study. Transplant International, 23 (s1). p. 14. ISSN 1432-2277

Kanwar, A, Ray, C, Noormohammed, S, Stamp, S, Ray, S, Sohrabi, Soroush, Shenton, B, Kesteven, B, Peaston, R, Libberecht, L and Carter, Noel (2010) Effects of Extra Corporeal Membrane Oxygenation (ECMO) on Liver Function and Histology, in a Porcine Model of Uncontrolled Non Heart Beating Donor (NHBD). Transplant International, 23 (s1). p. 5. ISSN 1432-2277

Khurram, M, Kanwar, A, Stamp, S, Asher, J, Wyrley-Birch, H, Gok, M, Shenton, B, Reddy, Mettu, Cunningham, Anne and Carter, Noel (2010) Machine Perfusion of Non Heart Beating Donor (NHBD) Kidneys: Continuous Versus Pulsatile Perfusion. Transplant International, 23 (s1). p. 8. ISSN 1432-2277

Kanwar, A, Carter, Noel, Cunningham, Anne and Talbot, D (2010) Non heartbeating donation – The heart of the matter. Current Anaesthesia & Critical Care, 21 (5-6). pp. 224-228. ISSN 0953-7112

Kibondo, Aimee, Talbot, D, Cullis-Hill, D, Maag, K, Cunningham, Anne and Carter, Noel (2010) Perfusates: Their properties and usage for the maintenance and storage of organs for transplantation. Current Anaesthesia & Critical Care, 21 (5-6). pp. 216-219. ISSN 0953-7112

Ray, C, Kanwar, A, Noormohamed, S, Navarro, A, Sohrabi, Soroush, Ray, S, Stamp, S, Wyrley-Birch, H, Carter, Noel and Cunningham, Anne (2010) Porcine Model of Extra-Corporeal Membrane Oxygenation (ECMO) in the Uncontrolled Non-Heart Beating Donor; Assessing Tissue Injury. Transplant International, 23 (s1). pp. 9-10. ISSN 1432-2277

Ray, C, Kanwar, A, Robson, L, Sohrabi, Soroush, Navarro, A P, Stamp, S, Noormohamed, M, Shenton, B, Carter, Noel, Cunningham, Anne and Talbot, D (2009) An Audit of Sudden Deaths in Accident and Emergency Unit as an on-Going Review of Potential Nhbd Donors. Transplant International, 22 (S2). pp. 106-107. ISSN 1432-2277

Navarro, Alex Patricio, Asher, J, Sohrabi, Soroush, Reddy, Mettu, Stamp, S, Carter, Noel and Talbot, David (2009) Peritoneal Cooling May Provide Improved Protection for Uncontrolled Donors after Cardiac Death: An Exploratory Porcine Study. American Journal of Transplantation, 9 (6). pp. 1317-1323. ISSN 1600-1643

Sohrabi, Soroush, Stamp, S, Peaston, B, Carter, Noel and Talbot, D (2009) Increased Pancreatic Iselt Cell Viability and Insulin Secretion after Enzymatic Digestion Using Edta as a Collagenase Inhibitor. Transplant International, 22 (s2). p. 9. ISSN 1432-2277

Kanwar, A, Ray, C, Wilson, C, Wyrley-Birch, H, Stamp, S, Navarro, A P, Shenton, B, Sohrabi, Soroush, Carter, Noel, Cunningham, Anne and Talbot, D (2009) Is a Low K(+) Organ Preservation Solution Better for Vascular Endothelium? Transplant International, 22 (S2). p. 348. ISSN 1432-2277

Ray, C, Kanwar, A, Stamp, S, Sohrabi, Soroush, Noormohamed, M, Navarro, A P, Carter, Noel, Cunningham, Anne, Shenton, B and Talbot, D (2009) Poor Perfusion of Retrieved Kidneys from Non-Heart Beating Donors - the Impact of Machine Perfusion. Transplant International, 22 (S2). p. 346. ISSN 1432-2277

Kanwar, A, Ray, C, Ray, S, Noormohamed, M, Stamp, S, Sohrabi, Soroush, Navarro, H, Wyrley-Birch, B, Shenton, A, Cunningham, Anne, Carter, Noel, White, S, Smith, Jim and Talbot, D (2009) Porcine Model of Extra-Corporeal Membrane Oxygenation (Ecmo) in the Uncontrolled Non-Heart Beating Donor (Nhbd); the Effect on Liver Viability. Transplant International, 22. p. 41. ISSN 1432-2277

Reddy, Mettu, Kibondo, Aimee, Aldibbiat, A, Stamp, S, Shenton, B, Shaw, J, Carter, Noel, Cunningham, Anne and Talbot, D (2009) Portal Venous Oxygen Persufflation for the Preservation of Non-Heart Beating Donor Pancreases Prior to Islet Isolaton. Transplant International, 22 (S2). p. 140. ISSN 1432-2277

Navarro, Alex Patricio, Sohrabi, Soroush, Reddy, Mettu, Carter, Noel, Ahmed, Ahmed and Talbot, David (2008) Dual transplantation of marginal kidneys from nonheart beating donors selected using machine perfusion viability criteria. Journal of Urology, 179 (6). pp. 2305-2309. ISSN 0022-5347

Carter, Noel, Arzoumanian, Hrant, Bennet, Terry and Watson, Zara (2004) Modulation of heparan sulfate/chemokine interactions using RNA interference. International Journal of Experimental Pathology, 85 (4). ISSN 09599673

Carter, Noel, Allenby, N A, O'Connor, N and Pragai, Z (2004) Post-transcriptional regulation of the Bacillus subtilis pst operon encoding a phosphate-specific ABC transporter. Microbiology, 150 (8). pp. 2619-2628. ISSN 00025461

Carter, Noel, Ali, S and Kirby, J A (2003) Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate. Journal of Cell Science, 116 (17). pp. 3591-3600. ISSN 00219533

Carter, Noel, Thwaites, David, Baillie, L W and Stephenson, K (2002) Optimization of the cell wall microenvironment allows increased production of recombinant Bacillus anthracis protective antigen from B. subtilis. Applied and Environmental Microbiology, 68 (1). pp. 227-234. ISSN 00992240

Conference or Workshop Item

Dawson, Peter, Jobson, Jill, Carter, Noel, Treumann, A., McGarry, Kenneth and Anderson, Rosaleen (2016) Investigating the protein differences between cystinotic and non-cystinotic cells. In: International Cystinosis Conference, 30 June - 3 July 2016, Valencia, Spain. (Submitted)

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, A and Anderson, Rosaleen (2013) A Quantitative Proteomic Investigation of Cystinotic Fibroblasts and Proximal Tubule Epithelial Cells using SILAC. In: Cystinosis Research Network Conference, 18 - 20 Jul 2013, Washington D.C., USA.

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, A and Anderson, Rosaleen (2012) A Quantitative Proteomic Comparison of Cystinotic and Control Fibroblasts. In: 7th International Cystinosis Conference, 28 June – 01 July 2012, Marriott Charles de Gaulle Hotel, Paris, France.

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, Achim and Anderson, Rosaleen (2011) Proteomic investigation of cystinotic cells and the effects of cysteamine treatment. In: Cystinosis Foundation UK Conference, 24 Sept 2011, Manchester Conference Centre, Manchester, UK.. (Unpublished)

Jobson, Jill, Carter, Noel, McGarry, Kenneth, Treumann, Achim and Anderson, Rosaleen (2011) Proteomic investigation of cystinotic cells and the effects of cysteamine treatment. In: Cystinosis Research Network 2011 Family Conference, 14 July 2011, Hotel Nikko, San Francisco, CA. (Unpublished)

Thesis

Ibrahim, Milad (2021) Investigating the relationship between Ambra1, Autophagy and Cell proliferation in Melanoma. Doctoral thesis, University of Sunderland.

This list was generated on Sun Dec 22 16:40:32 2024 GMT.
  • Molecular biology - qPCR, protein expression and purification
  • Tissue culture
  • Transplantation
  • Proteomics
  • MALDI-TOF mass spectrometry
  • Cell biology
  • Biological health and safety
  • Big Data Science ("omics")

Last updated 21 October 2024